Please use this identifier to cite or link to this item:
http://ricaxcan.uaz.edu.mx/jspui/handle/20.500.11845/1482
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor | 49237 | es_ES |
dc.contributor | 268446 | es_ES |
dc.contributor | 200970 | es_ES |
dc.contributor | 123645 | es_ES |
dc.contributor | 172879 | es_ES |
dc.coverage.spatial | Global | es_ES |
dc.creator | Martínez Fierro, Margarita de la Luz | - |
dc.creator | Garza Veloz, Idalia | - |
dc.creator | Gutierrez Arteaga, Christina | - |
dc.creator | Delgado Enciso, Iván | - |
dc.creator | Barbosa Cisneros, Olga Yadira | - |
dc.creator | Flores Morales, Virginia | - |
dc.creator | Hernández Delgadillo, Gloria Patricia | - |
dc.creator | Rocha Pizaña, María del Refugio | - |
dc.creator | Rodríguez Sánchez, Iram Pablo | - |
dc.creator | Badillo Almaráz, José Isaías | - |
dc.creator | Ortíz Rodríguez, José Manuel | - |
dc.creator | Castañeda Miranda, Rodrígo | - |
dc.creator | Solís Sánchez, Luis Octavio | - |
dc.creator | OrtÍz Castro, Yolanda | - |
dc.date.accessioned | 2020-04-01T17:51:16Z | - |
dc.date.available | 2020-04-01T17:51:16Z | - |
dc.date.issued | 2017-12-01 | - |
dc.identifier | info:eu-repo/semantics/publishedVersion | es_ES |
dc.identifier.issn | 1432-0711 | es_ES |
dc.identifier.uri | http://ricaxcan.uaz.edu.mx/jspui/handle/20.500.11845/1482 | - |
dc.description.abstract | Purpose: To perform serum microRNA expression profiling to identify members of chromosome 19 miRNA cluster involved in preeclampsia development. Methods: Serum chromosome 19 miRNA cluster microRNA expression profiling was evaluated at 12, 16, and 20 gestational weeks and at the time of preeclampsia diagnosis, in women who developed preeclampsia (WWD-PE; n = 16) and controls (n = 18) using TaqMan low density array plates. Results: A total of 51 chromosome 19 microRNA cluster members were evaluated. The circulating hsa-miRs 512-3p, 518f3p, 520c-3p, and 520d-3p, were differentially expressed between groups (P < 0.05). Compared with controls, serum levels of hsa-miR-518f-3p at 20 GW were useful for identifying WWD-Mild-PE (P = 0.035) and WWD-Severe-PE(P = 0.007). Conclusions: Serum hsa-miRs 512-3p, 518f-3p, 520c-3p, and 520d-3p, are differentially expressed between WWD-PE and controls and their role in the development of preeclampsia should be investigated further. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Springer | es_ES |
dc.relation | https://doi.org/10.1007/s00404-017-4611-6 | es_ES |
dc.relation.uri | generalPublic | es_ES |
dc.rights | Atribución-NoComercial-CompartirIgual 3.0 Estados Unidos de América | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/3.0/us/ | * |
dc.source | Arch Gynecol Obstet Vol. 297, pp. 365–371 | es_ES |
dc.subject.classification | INGENIERIA Y TECNOLOGIA [7] | es_ES |
dc.subject.other | Biomarkers | es_ES |
dc.subject.other | Preeclampsia | es_ES |
dc.subject.other | Placenta | es_ES |
dc.subject.other | Signaling pathway | es_ES |
dc.subject.other | MicroRNA | es_ES |
dc.title | Circulating levels of specific members of chromosome 19 microRNA cluster are associated with preeclampsia development | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
Appears in Collections: | *Documentos Académicos*-- Doc. en Ing. y Tec. Aplicada |
Files in This Item:
File | Description | Size | Format | |
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Circulating levels ofˇspecifc members ofˇchromosome 19 microRNA.pdf | 647,61 kB | Adobe PDF | View/Open |
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