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Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor | 208395 | es_ES |
dc.coverage.spatial | Global | es_ES |
dc.creator | Ochoa González, Fátima de Lourdes | - |
dc.creator | González Curiel, Irma Elizabeth | - |
dc.creator | Cervantes Villagrana, Alberto Rafael | - |
dc.creator | Fernández Ruiz, Julio Cesar | - |
dc.creator | Castañeda Delgado, Julio Enrique | - |
dc.date.accessioned | 2021-05-31T19:10:43Z | - |
dc.date.available | 2021-05-31T19:10:43Z | - |
dc.date.issued | 2020 | - |
dc.identifier | info:eu-repo/semantics/publishedVersion | es_ES |
dc.identifier.issn | 1875-5666 | es_ES |
dc.identifier.uri | http://ricaxcan.uaz.edu.mx/jspui/handle/20.500.11845/2541 | - |
dc.description.abstract | Diabetes is a chronic disease characterized by marked alterations in the metabolism of glucose and by high concentrations of glucose in the blood due to a decreased insulin production or resistance to the action of this hormone in peripheral tissues. The International Diabetes Federation estimates a global incidence of diabetes of about 10% in the adult population (20 - 79 years old), some 430 million cases reported worldwide in 2018. It is well documented that people with diabetes have a higher susceptibility to infectious diseases and therefore show higher morbidity and mortality compared to the non-diabetic population. Given that the innate immune response plays a fundamental role in protecting against invading pathogens through a myriad of humoral and cellular mechanisms, the present work makes a comprehensive review of the innate immune alterations in patients with type 2 diabetes mellitus (T2D) as well as a brief description of the molecular events leading or associated to such conditions. We show that in these patients a compromised innate immune response increases susceptibility to infections. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | BENTHAM SCIENCE | es_ES |
dc.relation | https://www.eurekaselect.com/node/185414/article/innate-immunity-alterations-in-type-2-diabetes-mellitus-understanding-infection-susceptibility | es_ES |
dc.relation.uri | generalPublic | es_ES |
dc.rights | Atribución-NoComercial-CompartirIgual 3.0 Estados Unidos de América | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/3.0/us/ | * |
dc.source | Current Molecular Medicine Vol.24, No.4, pp. 318-331 | es_ES |
dc.subject.classification | MEDICINA Y CIENCIAS DE LA SALUD [3] | es_ES |
dc.subject.other | Innate response | es_ES |
dc.subject.other | phagocytosis | es_ES |
dc.subject.other | Type 2 Diabetes Mellitus | es_ES |
dc.subject.other | infection | es_ES |
dc.subject.other | antimicrobial peptide | es_ES |
dc.subject.other | innate immune cells | es_ES |
dc.title | Innate Immunity Alterations in Type 2 Diabetes Mellitus: Understanding Infection Susceptibility | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
Appears in Collections: | *Documentos Académicos*-- M. en Ciencias y Tecnología Química |
Files in This Item:
File | Description | Size | Format | |
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Innate Immunity Alterations.pdf | 217,02 kB | Adobe PDF | View/Open |
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